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Emanuel Merck Lectureship

PROTACs and targeted protein degradation: A new therapeutic modality

Craig Crews

Lewis Cullman Professor of Molecular,

Cellular and Development Biology

and Professor of Chemistry and

Pharmacology, Yale (USA)

13. May 2024 16:15h 

Location: TU Darmstadt, Foyer of

Wilhelm-Köhler Saal (Room 284)

Hall S1/03, Hochschulstr. 1

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Scientific Symposium on Drug Delivery

Emerging approaches for drug delivery

Scientific symposium organized as part of the Merz Guest Professorhsip - renowned experts in the field of drug delivery present their latest results

09. Nov 2023 full day 

Location: Campus Friedberg, Biocenter, Lecture Hall B1, Max-von-Laue-Str. 9, 60439 Frankfurt

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PROXIDRUGS Lecture Series

Targeting protein modification and degradation

Edward W. Tate
GSK Chair in Chemical Biology, Imperial College
& The Francis Crick Institute
UK

06. Mar 2023 18:00h 

Location: GU Frankfurt - Uniklinik
Haus 22, Hörsaal 2

Hybrid Lecture

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The Tate group webpage

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PROXIDRUGS Lecture Series

Analyzing and targeting oncogenic transcription factors by directed protein degradation

Prof. Dr. Elmar Wolf
Julius-Maximilians-Universität Würzburg, Biozentrum, Würzburg, Germany

23. May 2022 15:00h 

Location: Lecture Hall H27B, Bldg. 27, Campus Niederrad

Hybrid Lecture

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PROXIDRUGS Lecture Series

Identifying fragments binding to the entire genome and proteome of SARS-CoV-2

Prof. Dr. Harald Schwalbe
Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University Frankfurt

27. Oct 2021 16:00h 

Location: UKF, auditorium 23-3

Hybrid Lecture

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PROXIDRUGS Lecture Series

Mapping the degradable kinome provides a resource for drug discovery

Fleur M. Ferguson
University of California San Diego,
La Jolla, US

 

01. Jun 2021 17:00h

Location: Virtual Lecture via Zoom

Virtual Lecture

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PROXIDRUGS Lecture Series

Regulation of histone methylation with methyl-lysine reader targeted degraders

Lindsey Ingerman James
University of North Carolina,
Chapel Hill, US

 

31. Mar 2021 16:00h

Location: Virtual Lecture via Zoom

Virtual Lecture

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PROXIDRUGS Lecture Series

Molecular mechanisms of small molecule mediated ubiquitin ligase targeting

Eric Fischer
Dana-Farber Cancer Institute & Harvard Medical School,
Boston,US

 

27. Oct 2020 16:30h

Location: Virtual Lecture via Zoom

Virtual Lecture

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PROXIDRUGS Lecture Series

Multispecific drugs, induced proximity, and the future of biopharmaceutical innovation

Ray Deshaies
Senior Vice President,
Global Research,
AMGEN, USA


25. Aug 2020 17:00h

Location: Virtual Lecture via Zoom

Virtual Lecture

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PROXIDRUGS Lecture Series

Chasing molecular glues and coping with resistance to degraders

Cristina Mayor-Ruiz

Institute for Research in Biomedicine (IRB), Barcelona

29. Jan 2024 16:00h 

Location: Virtual Lecture

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PROXIDRUGS Lecture Series

Spatiotemporal identification of binding sites with deep learning

Petr Popov
Tetra-d, München

18. Oct 2023 16:00h 

Location: Virtual Lecture

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1st German Chemical Biology Lectureship

Georg Winter

CeMM – The Research Center for Molecular Medicine 

of the Austrian Academy of Sciences

28. Nov 2022 17:00h 

Location: TU Darmstadt, Campus Lichtwiese, Alarich-Weiss-Straße 6, L203/06

Hybrid Lecture

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PROXIDRUGS Lecture Series

Transcription-coupled DNA repair:
Lessons learned on the ubiquitylation of complex substrates

Goran Kokic
Max Planck Institute for Biophysical Chemistry, Göttingen, Germany

18. Jan 2022 16:00h 

Location: Virtual Lecture

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PROXIDRUGS Lecture Series

Multidisciplinary approaches in the development of targeted protein degraders

Radoslaw Nowak
Dana-Farber Cancer Institute,
Harvard Medical School



14. Sep 2021 17:00h

Location: Virtual Meeting

Virtual Lecture

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TU Darmstadt Chemistry Seminar Series

Rapid response technologies for protein manufacturing and drug discovery

Prof. Dr. Bradley Pentelute
Massachusetts Institute of Technology Boston

 

25. May 2021 15:00h

Location: to be announced

Virtual Lecture

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TU Darmstadt Chemistry Seminar Series

Lessons from thalidomide analogues as prototype molecular glue degraders

Philip Chamberlain
Neomorph, Inc.


16. Feb 2021 17:00h

Location: Virtual Lecture via Zoom

Virtual Lecture

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PROXIDRUGS Lecture Series

Probing gene control via targeted protein degradation

Georg Winter
Center for Molecular Medicine of the Austrian Academy of Sciences (CeMM), Vienna, AT


29. Sep 2020 16:00h

Location: Virtual Lecture via Zoom; Meeting-ID: 962 0881 2086 Kenncode: 612251

Virtual Lecture

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PROXIDRUGS Lecture Series

Innovative approaches to proximity-inducing compound design: AI meets physics-based modeling

Alzbeta Tuerkova

Celeris Therapeutics, R&D Excellence Center, Graz, Austria

29. Nov 2023 16:00h 

Location: Virtual Lecture

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Perspectives in Medicine

Molecular origami: The TRiCky business of folding proteins in the cell

Judith Frydman
James H Clark Center
Stanford University, USA

Jochen Hückmann-Stiftungsgastprofessur für Forschungsexzellenz

02. Jun 2023 11:00h 

Location: Uni Campus Riedberg,
Otto-Stern-Zentrum, Hall H2

Download Announcement Flyer
Frydman lab

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PROXIDRUGS Lecture Series

Induced proximity medicines: Targeted protein degradation and beyond

Ryan Potts

Amgen, US

26. Sep 2022 16:15h 

Location: Lecture Hall H20-5, Bldg. 20, Campus Niederrad

Hybrid Lecture

Download Announcement
Download Agenda

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PROXIDRUGS Lecture Series

Design and synthesis of inhibitors targeting CNS kinases

Prof. Dr. Pierre Koch
Pharmazeutisches Institut, Lehrstuhl Pharm./Med. Chem. II, Universität Regensburg

22. Nov 2021 17:00h 

Location: Auditorium H2, Otto-Stern-Zentrum, Campus Riedberg

Virtual Lecture

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TU Darmstadt Chemistry Seminar Series

The coming of age of de novo protein design

Prof. Dr. David Baker
Washington University, Seattle

 

22. Jun 2021 17:00h

Location: Virtual Meeting

Virtual Lecture

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PROXIDRUGS Lecture Series

Large-scale chemoproteomic profiling surveys the degradable proteome for accelerated degrader development

Katherine A. Donovan
Dana-Farber Cancer Institute & Harvard Medical School,
Boston, US

 

18. May 2021 16:00h

Location: Virtual Lecture via Zoom

Virtual Lecture

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PROXIDRUGS Lecture Series

Reimagining druggability using chemoproteomic platforms

Daniel K. Nomura
University of California,
Berkeley, US


16. Nov 2020 17:00h

Location: Virtual Lecture via Zoom

Virtual Lecture

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PROXIDRUGS Lecture Series

Manipulating developmental pathways using proximity-inducing antibody modalities

Stephane Angers
Leslie Dan Faculty of Pharmacy,
University of Toronto,CA


01. Sep 2020 16:00h

Location: Virtual Lecture via Zoom

Virtual Lecture

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